Metria Berberine+
Metria Berberine+
Metria Berberine+ is a premium daily supplement built around a single non-negotiable: 1,200mg of pure berberine HCl per serving, squarely inside the 900–1,500mg range used across decades of peer-reviewed clinical research. Sourced from Berberis aristata root, third-party tested for identity, potency, heavy metals, and microbial safety, and manufactured in an FDA-registered, GMP-certified facility in the United States.
One bottle. Thirty servings. Backed by a 60-day empty-bottle guarantee.
Why 1,200mg of pure berberine HCl
Most berberine supplements on the market deliver between 200mg and 500mg per serving — well below the doses used in the studies they reference. Independent third-party testing has found that many berberine products contain less than their labeled potency.
Metria Berberine+ is built to the standard the research actually used. Each daily serving (two capsules) provides:
- 1,200mg pure berberine HCl — inside the 900–1,500mg clinical research range
- Berberis aristata root sourcing — a botanical source of berberine used in clinical research
- No proprietary blends. Every milligram is on the label.
- No fillers beyond what's required for capsule integrity
The form is berberine hydrochloride (HCl), the form most extensively studied in clinical research. We don't substitute or dilute.
How to take Metria Berberine+
Take two capsules daily with meals — typically one capsule with breakfast and one with dinner. Most clinical research used a 2–3 dose split throughout the day rather than a single dose, to maintain steady plasma berberine levels and minimize digestive sensitivity.
Berberine works best as a daily routine, not a one-time intervention. Most peer-reviewed studies show meaningful effects emerging over 8–12 weeks of consistent use, with continued benefits beyond that window. Plan for the long game.
Start with one capsule daily for the first 3–5 days if you're sensitive to supplements, then increase to the full serving.
Built on the research
Berberine is one of the most-studied natural compounds in modern metabolic research, with 50+ peer-reviewed human trials and multiple meta-analyses across a range of metabolic markers.
We don't make claims about what berberine will do for you specifically — individual results vary, and supplements aren't substitutes for medical care. We do publish the studies we built this product around, with direct links to PubMed, the original journals, and the relevant meta-analyses.
Key research bodies referenced:
- 37-RCT meta-analysis on metabolic markers (Frontiers in Pharmacology, 2022)
- 16-trial meta-analysis on lipid profile (Phytomedicine, 2018)
- 23-trial meta-analysis on body composition (International Journal of Obesity, 2025)
- Foundational AMPK mechanism research (2008; Frontiers in Pharmacology, 2023)
The Metria Standard
Every Metria product is built to the same five non-negotiables:
- Clinical-range dosing. Inside the range studied in peer-reviewed research, every time.
- Full label transparency. No proprietary blends. Every milligram on the label.
- Third-party verification. Every batch tested for identity, potency, heavy metals, and microbial safety.
- US-based GMP manufacturing. FDA-registered facility. Documentation available on request.
- A guarantee that means something. Open the bottle, take it for thirty days, return it for a full refund if it isn't right for you.
This is the only way we know how to build a supplement brand worth trusting.
Important safety information
Statements regarding dietary supplements have not been evaluated by the U.S. Food and Drug Administration. Metria Berberine+ is not intended to diagnose, treat, cure, or prevent any disease.
Consult your healthcare provider before taking Metria Berberine+ if you are pregnant, nursing, planning to become pregnant, under 18, or taking medication — particularly blood sugar medications, blood thinners, blood pressure medications, immunosuppressants, or antibiotics. Berberine has documented interactions with several drug classes.
Discontinue use and consult a healthcare provider if you experience any adverse reaction.